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Home > Blog > Narayana Health > Rhabdomyolysis Symptoms, Causes, and Treatment Options
Narayana HealthNephrology

Rhabdomyolysis Symptoms, Causes, and Treatment Options

by Narayana Health March 20, 2023
written by Narayana Health March 20, 2023
Rhabdomyolysis
Contents hide
1 Overview
2 Causes of Rhabdomyolysis
3 Symptoms of Rhabdomyolysis
4 How to Diagnose & Treat Rhabdomyolysis?
5 Preventive Measures to Help Prevent & Manage Rhabdomyolysis
6 When to consult a Doctor
7 Frequently Asked Questions about Rhabdomyolysis

Overview

Do you know what Rhabdomyolysis is? Rhabdomyolysis is a serious medical condition that must be identified and treated effectively. If not diagnosed or treated properly, this condition can lead to kidney failure, life-threatening electrolyte imbalances, and complications in different body areas.

Rhabdomyolysis is a medical syndrome that occurs when muscle fibres break down rapidly. As a result, it releases toxic proteins into the bloodstream, which can cause serious damage to other organ systems and the kidneys. Symptoms of this condition include severe muscle pain, weakness, swelling, dark urine, and fatigue.

Rhabdomyolysis is an uncommon but dangerous clinical syndrome with devastating consequences if not managed adequately. This article will discuss the causes, symptoms, and treatments for Rhabdomyolysis. 

Causes of Rhabdomyolysis

Below are the pointers that show the causes of Rhabdomyolysis :

  • Crushing injuries: Rhabdomyolysis is often caused by traumatic injuries such as those sustained in a car accident or fall, where the muscles are crushed or compressed.
  • Severe muscle strain: Prolonged and vigorous physical exercise can sometimes lead to overextended muscle fibres, leading to rhabdomyolysis in some people.
  • Electric shock: Exposure to high-voltage electric shocks can lead to rhabdomyolysis due to the severe trauma suffered by the body’s muscle fibres.
  • Infections: Bacterial infections such as Legionnaires’ disease and toxoplasmosis may cause rhabdomyolysis through inflammation of the muscles and other underlying issues with organ systems in the body.
  • Medication use: Certain medications, such as statins, antipsychotics, cocaine, and alcohol, can all lead to rhabdomyolysis when taken in excess amounts or combined with certain drugs like antibiotics.
  • Dehydration: Not receiving enough water or electrolytes can put someone at risk for developing this complication, especially if they engage in vigorous physical activity that causes their core body temperature to rise significantly over a short period.

Now let’s understand the symptoms that lead to Rhabdomyolysis, and you must get yourself treated right away. We have it covered in the next segment. 

Symptoms of Rhabdomyolysis

Check out the Rhabdomyolysis symptoms to be ready for the diagnosis:

  • Muscle soreness, stiffness, and swelling
  • Dark red or brown urine
  • Abdominal pain or tenderness
  • Weakness, numbness, or decreased reflexes in the legs and arms
  • Fatigue and overall body discomfort
  • Fever and chills
  • Nausea and vomiting
  • Rapid heart rate (tachycardia)
  • Light-headedness, syncope, or confusion

As and when you experience any of the above symptoms, get diagnosed and treated quickly. Below segment can help you in the process. Check it out:

How to Diagnose & Treat Rhabdomyolysis?

Below is the process involved in the diagnosis and treatment of Rhabdomyolysis

  • Diagnosing rhabdomyolysis requires a physical exam and a medical history to identify potential signs or symptoms. Blood tests may also be ordered to measure levels of muscle-related proteins such as creatine kinase (CK) or myoglobin, which can indicate the presence of rhabdomyolysis.
  • Rhabdomyolysis treatment depends on the underlying cause but can include rest, rehydration through intravenous fluids, and medications to reduce pain and inflammation. Avoiding strenuous physical activity while recovering from rhabdomyolysis is important to allow the muscles time to recover and heal properly.
  • Dialysis may also be needed in more severe cases as it helps remove waste products from muscle cells broken down due to extreme exertion or injury. In some cases, surgery may be necessary if an underlying medical condition needs treatment for recovery from rhabdomyolysis to occur effectively.
  • Other treatments for rhabdomyolysis may include supplementation with electrolytes and vitamins, as well as antibiotic medications if an infection is present or suspected.

To recover fully, you must follow proper precautions to protect and manage this severe condition without any hassle. Below we have it covered for you. Check it out.

Preventive Measures to Help Prevent & Manage Rhabdomyolysis

  • Maintain adequate hydration, particularly when engaging in strenuous activity.
  • Avoid excessive levels of exertion or physical activity.
  • Recognize signs of rhabdomyolysis early and seek treatment as appropriate.
  • Take breaks during prolonged periods of muscular activity and stretch the muscles to reduce fatigue and cramping.

When to consult a Doctor

You can also get in touch with the expert Nephrology doctors at Narayana Healthcare based in your city to get immediate attention and medical support during injuries, health disorders or any other health concern.

  • Best Nephrologists in Delhi
  • Top Nephrologists in Ahmedabad
  • Best Nephrologists in Bangalore
  • Top Nephrologists in Jaipur
  • Best Nephrologists in Kolkata

In conclusion, rhabdomyolysis is a serious condition that usually develops due to muscle trauma or injury and can lead to kidney failure if left untreated. It is characterised by symptoms such as muscle pain and weakness, dark-coloured urine, swelling in the extremities, nausea, vomiting, confusion, and fever. The causes of rhabdomyolysis are varied but often involve extensive physical exertion with inadequate nutrition or rehydration, taking certain medications or illegal drugs, exposure to extreme temperatures, and other health conditions. 

Treatment for Rhabdomyolysis complications typically involves aggressive hydration with intravenous fluids and supportive care for any complications that may occur. It’s important to remember that if you think you may be suffering from this condition, it is best to seek medical attention immediately to prevent further damage.

Frequently Asked Questions about Rhabdomyolysis

Q. What is rhabdomyolysis, and how does it affect the kidneys?
A. Rhabdomyolysis is when muscle tissue breaks down, releasing its contents, including the enzyme creatine kinase, into the bloodstream. This can lead to kidney failure because of overworked kidneys and damage to their cells caused by creatine kinase.

Q. What are the common causes of rhabdomyolysis, and how can it be prevented?
A. Common causes of rhabdomyolysis include injury and trauma, severe exertion (extreme exercise), extreme heat exposure and dehydration, certain medications/illicit drugs, infections, and metabolic and endocrine disorders. 

Q. What are the symptoms of rhabdomyolysis, and how is it diagnosed?
A. The symptoms of rhabdomyolysis include muscle pain, weakness, dark urine, and fever. It is diagnosed through a physical exam and laboratory tests that measure abnormal levels of enzymes and proteins in the blood. A doctor may also order imaging tests such as an MRI to confirm the diagnosis.

Q. How is rhabdomyolysis treated, and what are the possible complications?
A. Rhabdomyolysis is treated with rest, hydration, supportive care, medications to reduce pain and cramping, and sometimes dialysis. Possible complications include kidney damage, electrolyte abnormalities, muscle scarring or contractures, compartment syndrome, nerve injury, and cardiac arrest.

Q. Are certain populations more susceptible to rhabdomyolysis than others?
A. Yes, certain populations are more at risk of developing rhabdomyolysis than others. For example, those with muscular dystrophy, kidney or liver disease, or uncontrolled diabetes may be at greater risk due to the health complications associated with these conditions. 

Q. How long does it take for rhabdomyolysis to develop, and what are the early warning signs?
A. Rhabdomyolysis usually develops within 4-6 hours after exerting excessive muscle activity, and the early warning signs include severe muscle pain, weakness, stiffness, swelling, and dark red or brown urine.

Reference:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365849/
https://www.webmd.com/a-to-z-guides/rhabdomyolysis-symptoms-causes-treatments
https://my.clevelandclinic.org/health/diseases/21184-rhabdomyolysis
https://www.healthline.com/health/rhabdomyolysi

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